Diagnostic, predictive and prognostic biomarkers in systemic lupus erythematosus: current insights
J Lindblom, C Mohan, I Parodis - Current Opinion in …, 2022 - journals.lww.com
J Lindblom, C Mohan, I Parodis
Current Opinion in Rheumatology, 2022•journals.lww.comNGAL holds promise as a versatile biomarker in SLE whereas urine ALCAM, CD163 and
VCAM-1 displayed good performance as biomarkers in LN. The overall lack of concerted
corroboration of leading candidates across multiple cohorts and diverse populations leaves
the current biomarker landscape in SLE in an urgent need for further survey and systematic
validation.
VCAM-1 displayed good performance as biomarkers in LN. The overall lack of concerted
corroboration of leading candidates across multiple cohorts and diverse populations leaves
the current biomarker landscape in SLE in an urgent need for further survey and systematic
validation.
Summary
NGAL holds promise as a versatile biomarker in SLE whereas urine ALCAM, CD163 and VCAM-1 displayed good performance as biomarkers in LN. The overall lack of concerted corroboration of leading candidates across multiple cohorts and diverse populations leaves the current biomarker landscape in SLE in an urgent need for further survey and systematic validation.
Lippincott Williams & Wilkins