Measurement of energy metabolism in explanted retinal tissue using extracellular flux analysis

JR Millman, T Doggett, C Thebeau, S Zhang… - JoVE (Journal of …, 2019 - jove.com
High acuity vision is a heavily energy-consuming process, and the retina has developed
several unique adaptations to precisely meet such demands while maintaining transparency
of the visual axis. Perturbations to this delicate balance cause blinding illnesses, such as
diabetic retinopathy. Therefore, the understanding of energy metabolism changes in the
retina during disease is imperative to the development of rational therapies for various
causes of vison loss. The recent advent of commercially-available extracellular flux …